Assistant Professor and Co-director Biochemistry Program
Dr. Masterson is an Assistant Professor of Chemistry at Hamline University. He received his doctoral degree in Chemistry in 2008 at the University of Minnesota. Since beginning his PhD, his work has led to over 20 publications, highlighted in journals such as Nature and the Proceedings of the National Academy of Science. This research mainly aimed at studies of protein-protein interactions in the context of heart muscle contractility, specifically those that are correlated with dilated cardiomyopathy. Dr. Masterson is now focused on understanding the mechanism behind protein dysfunction, leading to Alzheimer's disease or associated with Chronic Traumatic Encephalopathy from the head injuries of athletes. Using a battery of techniques, including thermal calorimetry, steady-state kinetics, Molecular Dynamics simulations, and NMR spectroscopy, Dr. Masterson is working to establish a general framework for the physical basis of protein aggregation. His long term goal is to establish a clearer understanding of the connection between protein structure, dynamics, and function, particularly in the context of disease.
Dr. Masterson strives to bring a sense of energy, excitement, and real world connection to his art of teaching. He enjoys incorporating new technologies in his classroom at the introductory and advanced levels, and working closely with students to understand science at the interface of chemistry, biology, and physics.
“I want to inspire students to think like scientists and work towards an ability to contribute to our body of knowledge. Ultimately, I want students to see that the details at the molecular level are pivotal for providing an understanding of biological function and disease.”
-Dr. L.R. Masterson
Masterson Research Website