Mitambo and Kiemele won, 8-3, at third doubles.
At second doubles, Anna Yarbrough (Fy., Minneapolis, Minn.) and Kelsey Eatherton (So., White Bear Lake, Minn.) fought to a 4-8 loss.
Eatherton also battled in her fourth singles match, winning the first set before falling in a super-breaker, 6-4, 2-6, 5-10.
The Pipers drop to 0-2, 0-1 MIAC with their first conference match of the season. The Knights are 2-0, 1-0 MIAC.
The Pipers will play St. Thomas at Baseline Tennis Center on Saturday, February 7, at 5:00 p.m.