The Stars, who were the 2008 Northern Athletics Conference champions and a 2008 NCAA tournament team, scored first at 31 minutes. The hosts then took a 2-0 lead nine minutes after halftime.
Matt Warhol (Sr., Andover, Minn.) scored the Pipers' goal with seven minutes to play in the game. First-year Sam Slagle (Appleton, Wis.) was credited with the assist.
The goal came on one of Hamline's two shots on goal while Dominican put five shots on net.
The Pipers open the season at 0-1 overall with the non-conference loss. They remain on the road and travel to North Central (Illinois) tomorrow, Wednesday, September 2, for a 5 pm start.