Dan Andersen (Jr., Minneapolis, Minn.) and Carl Hipp (So., Little Canada, Minn.) scored the opening baskets of the contest, but the early 4-0 lead quickly dissolved, and it would be the only lead the visitors would hold.
The Pipers trailed 35-21 at halftime.
Hipp led the Pipers with 12 points and 10 rebounds (three offensive, seven defensive). Andersen finished with nine points.
The Pipers now stand at 3-10, 2-7 MIAC with the conference loss. The Johnnies move to 7-7, 5-4 MIAC. The Pipers will return home on Monday, January 19, to take on St. Thomas in the final game of the first half of the conference season. Tip-off is set for 7:30 p.m.