St. Thomas won by set scores of 25-11, 25-17, 25-11.
The Tommies took control early in all three sets, letting Hamline hold just a 1-0 lead to start the second set.
Sam Greeney-Hamlin (Fy., St. Cloud, Minn.) had eight kills to lead the Pipers while Heidi Larsen (Sr., Andover, Minn.) had 21 digs.
St. Thomas was led by 13 kills and 17 digs from Katie Bonine.
The Pipers fall to 9-12, 2-4 MIAC while the Tommies are now 17-3, 4-1 MIAC. Hamline will travel to Bethany Lutheran on Monday, October 11, for a 7:00 p.m. match in their next contest.